New investigation results, 'Pegylated immuno-lipopolyplexes: A novel non-viral gene delivery system for liver cancer therapy,' are detailed in a study published in Journal of Controlled Release. According to recent research from People's Republic of China, "In this study, pegylated immuno-lipopolyplexes (PILP), a novel and efficient gene delivery system was developed by employing DNA/polyethylenimine (PEI 25 kDa) polyplexes, as well as anionic liposomes composed of POPC, (DSPE)-PEG2000 and (DSPE)-PEG2000-biotin, at five different lipid/DNA molar ratios (50/1, 90/1, 130/1, 170/1 and 210/1), and by using streptavidin-monoclonal antibody conjugating through the biotin group located at the …
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